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| Cat.No | ACP21255 | Target Name | NME6 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-186 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75414 |
|---|
Uniprot Id
O75414
Target Species
Human
Target Name
NME6
Target Full Name
Nucleoside diphosphate kinase 6
Target Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Target Protein Families
NDK family
Target Tissue Specificity
Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.
Target Synonyms
Inhibitor of p53 induced apoptosis alpha ; Inhibitor of p53-induced apoptosis-alpha; IPIA ALPHA; IPIA-alpha; NDK 6; NDK6_HUMAN; NDP kinase 6; NM23 H6 ; nm23-H6; NM23H6 ; Nme6; Nucleoside diphosphate kinase 6; OTTHUMP00000164810; OTTHUMP00000210736; OTTHUMP00000210737; OTTHUMP00000210738; OTTHUMP00000210741; OTTHUMP00000210742; OTTHUMP00000210744; OTTHUMP00000210745
Target Background
Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).
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