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Recombinant Human Osteopetrosis-associated transmembrane protein 1 (OSTM1), Truncated

ACP15624

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Specifications

Cat.No	ACP15624	Target Name	OSTM1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q86WC4

Background Information

Uniprot Id

Q86WC4
Target Species

Human
Target Name

OSTM1
Target Full Name

Osteopetrosis-associated transmembrane protein 1
Target Function

Required for osteoclast and melanocyte maturation and function.
Target Involvement

Osteopetrosis, autosomal recessive 5 (OPTB5)
Target Subcellular Location

Lysosome membrane; Single-pass type I membrane protein. Note=Requires CLCN7 to travel to lysosomes.
Target Protein Families

OSTM1 family
Target Synonyms

Chloride channel 7 beta subunit; GAIP-interacting protein N terminus; GIPN; GL; Grey lethal osteopetrosis; HSPC019; OPTB5; Osteopetrosis-associated transmembrane protein 1; Ostm1; OSTM1_HUMAN; OTTHUMP00000016938; OTTHUMP00000196342
Target Background

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.

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Recombinant Human Osteopetrosis-associated transmembrane protein 1 (OSTM1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Osteopetrosis-associated transmembrane protein 1 (OSTM1), Truncated Now

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