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Recombinant Human p53 apoptosis effector related to PMP-22 (PERP), Truncated

ACP05916

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Specifications

Cat.No	ACP05916	Target Name	PERP
Target Synonyms	PERP; KCP1; KRTCAP1; PIGPC1; THW; p53 apoptosis effector related to PMP-22; Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THW	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96FX8

Background Information

Uniprot Id

Q96FX8
Target Species

Human
Target Name

PERP
Target Full Name

p53 apoptosis effector related to PMP-22
Target Function

Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.
Target Subcellular Location

Cell junction, desmosome. Cell membrane; Multi-pass membrane protein.
Target Protein Families

TMEM47 family
Target Tissue Specificity

Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.
Target Synonyms

PERP; KCP1; KRTCAP1; PIGPC1; THW; p53 apoptosis effector related to PMP-22; Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THW
Target Background

Involved in activation of cysteine-type endopeptidase activity. Predicted to be located in plasma membrane. Predicted to be active in cell-cell junction. Implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques.

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Recombinant Human p53 apoptosis effector related to PMP-22 (PERP), Truncated

Specifications

Immunogen Information

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