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Recombinant Human Peroxisomal multifunctional enzyme type 2 (HSD17B4)

ACP04887

Number
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Specifications


Cat.No ACP04887 Target NameHSD17B4
Target Synonymsperoxisomal; DBP; DBPFormLiquid or Lyophilized powder
Expression SystemYeastExpression Range1-736aa
Mol Weight81.7kDaProtein LengthFull length
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP51659
Background Information
  • Uniprot Id

    P51659

  • Target Species

    Human

  • Target Name

    HSD17B4

  • Target Full Name

    Peroxisomal multifunctional enzyme type 2

  • Target Function

    Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids. Catalyzes the formation of 3-ketoacyl-CoA intermediates from straight-chain, 2-methyl-branched-chain fatty acids bile acid intermediates. With EHHADH, catalyzes the hydration of trans-2-enoyl-CoA and the dehydrogenation of 3-hydroxyacyl-CoA, but with opposite chiral specificity.

  • Target Involvement

    D-bifunctional protein deficiency (DBPD); Perrault syndrome 1 (PRLTS1)

  • Target Subcellular Location

    Peroxisome.

  • Target Protein Families

    Short-chain dehydrogenases/reductases (SDR) family

  • Target Tissue Specificity

    Present in many tissues with highest concentrations in liver, heart, prostate and testis.

  • Target Research Area

    Cancer

  • Target Synonyms

    12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; 17 beta HSD 4; 17 beta HSD IV; 17 beta hydroxysteroid dehydrogenase 4; 17-beta-HSD 4; 17-beta-hydroxysteroid dehydrogenase 4; 17beta estradiol dehydrogenase type IV; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase; 3-alpha; 7-alpha; Beta hydroxyacyl dehydrogenase; Beta keto reductase; D 3 hydroxyacyl CoA dehydratase; D bifunctional protein; D bifunctional protein peroxisomal ; D-3-hydroxyacyl CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein; D-bifunctional protein; D-bifunctional protein, peroxisomal; DBP; DBP, peroxisomal; DHB4_HUMAN; EDH17B4; Enoyl-CoA hydratase 2; Hsd17b4; Hydroxysteroid (17-beta) Dehydrogenase 4; MFE 2; MFE-2; MPF-2; Multifunctional protein 2; Peroxisomal multifunctional enzyme type 2; Peroxisomal multifunctional protein 2; PRLTS1; SDR8C1; Short chain dehydrogenase/reductase family 8C member 1

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