Recombinant Human PERQ amino acid-rich with GYF domain-containing protein 2 (GIGYF2), Truncated

ACP08918

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Specifications

Cat.No	ACP08918	Target Name	GIGYF2
Target Synonyms	GIGYF2; KIAA0642; PERQ2; TNRC15GRB10-interacting GYF protein 2; PERQ amino acid-rich with GYF domain-containing protein 2; Trinucleotide repeat-containing gene 15 protein	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6Y7W6

Background Information

Uniprot Id

Q6Y7W6
Target Species

Human
Target Name

GIGYF2
Target Full Name

GRB10-interacting GYF protein 2
Target Function

Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation. In the 4EHP-GYF2 complex, acts as a factor that bridges EIF4E2 to ZFP36/TTP, linking translation repression with mRNA decay. Also recruits and bridges the association of the 4EHP complex with the decapping effector protein DDX6, which is required for the ZFP36/TTP-mediated down-regulation of AU-rich mRNA. May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors.
Target Involvement

Parkinson disease 11 (PARK11)
Target Protein Families

GIGYF family
Target Research Area

Signal Transduction
Target Synonyms

GIGYF2; KIAA0642; PERQ2; TNRC15GRB10-interacting GYF protein 2; PERQ amino acid-rich with GYF domain-containing protein 2; Trinucleotide repeat-containing gene 15 protein

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Recombinant Human PERQ amino acid-rich with GYF domain-containing protein 2 (GIGYF2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human PERQ amino acid-rich with GYF domain-containing protein 2 (GIGYF2), Truncated Now

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