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Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1), Truncated

ACP13322

Number
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Specifications


Cat.No ACP13322 Target NamePREX1
Target Synonyms4, 4; 5)-dependent Rac exchanger 1; KIAA1415; OTTHUMP00000031228; P REX1; P Rex1 protein like; P-Rex1; Phosphatidylinositol 3, 5 trisphosphate dependent Rac exchange factor 1; Phosphatidylinositol 3, 5 trisphosphate dependent Rac exchanger 1 protein; Phosphatidylinositol 3, 5 trisphosphate dependent Rac exchanger 1; Phosphatidylinositol 3, 5-trisphosphate-dependent Rac exchanger 1 protein; Prex1; PREX1_HUMAN; PtdIns(3; PtdIns(3, 5) dependent Rac exchanger 1; SET domain containing 6; Setd6FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TCU6
Background Information
  • Uniprot Id

    Q8TCU6

  • Target Species

    Human

  • Target Name

    PREX1

  • Target Full Name

    Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

  • Target Function

    Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

  • Target Subcellular Location

    Cytoplasm, cytosol. Cell membrane. Note=Mainly cytosolic. Some amount is apparently associated to the plasma membrane.

  • Target Tissue Specificity

    Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.

  • Target Synonyms

    4; 5)-dependent Rac exchanger 1; KIAA1415; OTTHUMP00000031228; P REX1; P Rex1 protein like; P-Rex1; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 1; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1; Phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchanger 1 protein; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; Prex1; PREX1_HUMAN; PtdIns(3; PtdIns(3,4,5) dependent Rac exchanger 1; SET domain containing 6; Setd6

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