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Recombinant Human Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C)

ACP14816

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14816 Target NamePIP4K2C
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range2-421Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TBX8
Background Information
  • Uniprot Id

    Q8TBX8

  • Target Species

    Human

  • Target Name

    PIP4K2C

  • Target Full Name

    Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

  • Target Function

    Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3.

  • Target Subcellular Location

    Endoplasmic reticulum. Cytoplasm.

  • Target Synonyms

    Phosphatidylinositol 4 phosphate 5 kinase; Phosphatidylinositol 4 phosphate 5 kinase type II gamma; Phosphatidylinositol-5-phosphate 4-kinase type II gamma; Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma; PI(5)P 4-kinase type II gamma; PI42C_HUMAN; Pip4k2c; PIP4KII-gamma; PIP5K2C

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