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| Cat.No | ACP14816 | Target Name | PIP4K2C |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-421 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8TBX8 |
|---|
Uniprot Id
Q8TBX8
Target Species
Human
Target Name
PIP4K2C
Target Full Name
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Target Function
Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3.
Target Subcellular Location
Endoplasmic reticulum. Cytoplasm.
Target Synonyms
Phosphatidylinositol 4 phosphate 5 kinase; Phosphatidylinositol 4 phosphate 5 kinase type II gamma; Phosphatidylinositol-5-phosphate 4-kinase type II gamma; Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma; PI(5)P 4-kinase type II gamma; PI42C_HUMAN; Pip4k2c; PIP4KII-gamma; PIP5K2C
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