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| Cat.No | ACP13959 | Target Name | SERBP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-408 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NC51 |
|---|
Uniprot Id
Q8NC51
Target Species
Human
Target Name
SERBP1
Target Full Name
SERPINE1 mRNA-binding protein 1
Target Function
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation.
Target Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Target Tissue Specificity
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
Target Synonyms
CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; DKFZp564M2423; FLJ90489; HABP4L; PAI 1 mRNA binding protein; PAI RBP1; PAI-RBP1; PAI1 RNA-binding protein 1; PAIRB_HUMAN; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; Plasminogen activator inhibitor 1 RNA-binding protein; Serbp1; SERPINE1 mRNA binding protein 1; SERPINE1 mRNA-binding protein 1
Target Background
Enables SUMO binding activity; mRNA 3'-UTR binding activity; and ribosome binding activity. Involved in PML body organization. Located in cytosol and nucleus.
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