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Recombinant Human Pleiotropic regulator 1 (PLRG1)

ACP20778

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20778 Target NamePLRG1
Target SynonymsArabidopsis, Arabidopsis); Pleiotropic regulator 1; PLRG 1; PLRG1; PLRG1_HUMAN; PRL 1; PRL1; PRL1, Cwc1; MGC110980; pleiotropic regulator 1 (PRL1 homolog, homolof of; PRP46; PRPF46; TANGO4; transport and golgi organization 4 homologFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-514
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO43660
Background Information
  • Uniprot Id

    O43660

  • Target Species

    Human

  • Target Name

    PLRG1

  • Target Full Name

    Pleiotropic regulator 1

  • Target Function

    Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.

  • Target Subcellular Location

    Nucleus. Nucleus speckle.

  • Target Protein Families

    WD repeat PRL1/PRL2 family

  • Target Synonyms

    Cwc1; MGC110980; pleiotropic regulator 1 (PRL1 homolog, Arabidopsis); Pleiotropic regulator 1; PLRG 1; PLRG1; PLRG1_HUMAN; PRL 1; PRL1; PRL1, Arabidopsis, homolof of; PRP46; PRPF46; TANGO4; transport and golgi organization 4 homolog

  • Target Background

    This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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