Recombinant Human Polycystic kidney disease 2-like 1 protein (PKD2L1), Truncated

Cat.No	ACP05782	Target Name	PKD2L1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP05782

Target Name

PKD2L1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9P0L9

Background Information

Uniprot Id

Q9P0L9
Target Species

Human
Target Name

PKD2L1
Target Full Name

Polycystin-2-like protein 1
Target Function

Pore-forming subunit of a heterotetrameric, non-selective cation channel that is permeable to Ca(2+). Pore-forming subunit of a calcium-permeant ion channel formed by PKD1L2 and PKD1L1 in primary cilia, where it controls cilium calcium concentration, but does not affect cytoplasmic calcium concentration. The channel formed by PKD1L2 and PKD1L1 in primary cilia regulates sonic hedgehog/SHH signaling and GLI2 transcription. Pore-forming subunit of a channel formed by PKD1L2 and PKD1L3 that contributes to sour taste perception in gustatory cells. The heteromeric channel formed by PKD1L2 and PKD1L3 is activated by low pH, but opens only when the extracellular pH rises again. May play a role in the perception of carbonation taste. May play a role in the sensory perception of water, via a mechanism that activates the channel in response to dilution of salivary bicarbonate and changes in salivary pH.
Target Subcellular Location

Cell projection, cilium membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle.
Target Protein Families

Polycystin family
Target Tissue Specificity

Detected in taste bud cells in fungiform papillae (at protein level). Ubiquitous. Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. Isoform 4 appears to be expressed only in transformed lymphoblasts.
Target Synonyms

B830002B15; BC046386; PCL; PK2L1; PK2L1_HUMAN; PKD2L; PKD2L1; PKDL; Polycystic kidney disease 2 like 1; Polycystic kidney disease 2 like 1 protein; Polycystic kidney disease 2-like 1 protein; Polycystin L; Polycystin-2 homolog; Polycystin-2L1; Polycystin-L; Polycystin-L1; Transient receptor potential cation channel subfamily P member 3; TRPP3

Recombinant Human Polycystic kidney disease 2-like 1 protein (PKD2L1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Polycystic kidney disease 2-like 1 protein (PKD2L1), Truncated Now

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