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| Cat.No | ACP10025 | Target Name | KCNE5 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UJ90 |
|---|
Uniprot Id
Q9UJ90
Target Species
Human
Target Name
KCNE5
Target Full Name
Potassium voltage-gated channel subfamily E regulatory beta subunit 5
Target Function
Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1.
Target Involvement
Alport syndrome with mental retardation, midface hypoplasia and elliptocytosis (ATS-MR)
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Potassium channel KCNE family
Target Tissue Specificity
Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta.
Target Synonyms
KCNE5; AMMECR2; KCNE1L; Potassium voltage-gated channel subfamily E regulatory beta subunit 5; AMME syndrome candidate gene 2 protein; Potassium channel subunit beta MiRP4; Potassium voltage-gated channel subfamily E member 1-like protein
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