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| Cat.No | ACP12300 | Target Name | WDR33 |
|---|---|---|---|
| Target Synonyms | WD repeat containing protein 33; WD repeat domain 33; WD repeat-containing protein 33; WD repeat-containing protein WDC146; WDC146; WDR 33; WDR33; WDR33_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9C0J8 |
|---|
Uniprot Id
Q9C0J8
Target Species
Human
Target Name
WDR33
Target Full Name
pre-mRNA 3' end processing protein WDR33
Target Function
Essential for both cleavage and polyadenylation of pre-mRNA 3' ends.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Most highly expressed in testis.
Target Synonyms
WD repeat containing protein 33; WD repeat domain 33; WD repeat-containing protein 33; WD repeat-containing protein WDC146; WDC146; WDR 33; WDR33; WDR33_HUMAN
Target Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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