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| Cat.No | ACP03042 | Target Name | PFDN1 |
|---|---|---|---|
| Target Synonyms | PDF; PFD1; PFD1_HUMAN; pfdn1; Prefoldin 1; Prefoldin subunit 1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 2-122 |
| Mol Weight | 41.1kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O60925 |
|---|
Uniprot Id
O60925
Target Species
Human
Target Name
PFDN1
Target Full Name
Prefoldin subunit 1
Target Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Target Protein Families
Prefoldin subunit beta family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
PDF; PFD1; PFD1_HUMAN; pfdn1; Prefoldin 1; Prefoldin subunit 1
Target Background
This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
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