Recombinant Human PRELI domain-containing protein 1, mitochondrial (PRELID1)

Cat.No	ACP09650	Target Name	PRELID1
Target Synonyms	chicken, homolog of; Px19-like protein; SBBI12	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	36-219
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP09650

Target Name

PRELID1

Target Synonyms

chicken, homolog of; Px19-like protein; SBBI12

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

36-219

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9Y255

Background Information

Uniprot Id

Q9Y255
Target Species

Human
Target Name

PRELID1
Target Full Name

PRELI domain-containing protein 1, mitochondrial
Target Function

Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.
Target Subcellular Location

Mitochondrion. Mitochondrion intermembrane space.
Target Tissue Specificity

Highly expressed in fetal liver; less expressed in fetal brain, lung, and kidney. At the adult stage, expression is drastically reduced in the liver but highly expressed in the spleen, brain, lung, lymph nodes and peripheral blood leukocytes.
Target Research Area

Metabolism
Target Synonyms

25 kDa protein of relevant evolutionary and lymphoid interest; CGI 106; MGC87972; mitochondrial; PRELI; PRELI domain containing 1; PRELI domain containing protein 1; PRELI domain containing protein 1 mitochondrial; PRELI domain-containing protein 1; PRELID 1; PRELID1; PRLD1_HUMAN; Protein of relevant evolutionary and lymphoid interest; PX 19; PX19; Px19 like protein; Px19, chicken, homolog of; Px19-like protein; SBBI12
Target Background

This gene encodes a member of the late embryogenesis abundant motif-containing protein family. The encoded protein is localized to mitochondria and may function as a cytoprotectant by regulating cell death and differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. Several related pseudogenes have been identified.

Recombinant Human PRELI domain-containing protein 1, mitochondrial (PRELID1)

Specifications

Immunogen Information

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