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| Cat.No | ACP18703 | Target Name | PNOC |
|---|---|---|---|
| Target Synonyms | included; nocistatin; Npnc1; OFQ; OFQ/N; Orphanin FQ; Orphanin FQ2; Pnoc; PNOC_HUMAN; ppN/OFQ; PPNOC; pre-pro-N/OFQ; prepronociceptin; pronociceptin; Propronociceptin, N/OFQ; N23K; N23K/N27K; Nociceptin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 98-127 |
| Protein Length | Cytoplasmic Domain | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13519 |
|---|
Uniprot Id
Q13519
Target Species
Human
Target Name
PNOC
Target Full Name
Prepronociceptin
Target Function
Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.; Blocks nociceptin action in pain transmission by inhibiting nociceptin-induced hyperalgesia and allodynia.; Has potent analgesic activity.
Target Subcellular Location
Secreted.
Target Protein Families
Opioid neuropeptide precursor family
Target Tissue Specificity
Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation.
Target Synonyms
N/OFQ; N23K; N23K/N27K; Nociceptin, included; nocistatin; Npnc1; OFQ; OFQ/N; Orphanin FQ; Orphanin FQ2; Pnoc; PNOC_HUMAN; ppN/OFQ; PPNOC; pre-pro-N/OFQ; prepronociceptin; pronociceptin; Propronociceptin
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