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| Cat.No | ACP08091 | Target Name | PLPP6 |
|---|---|---|---|
| Target Synonyms | PLPP6; PPAPDC2; Phospholipid phosphatase 6; Phosphatidic acid phosphatase type 2 domain-containing protein 2; PPAP2 domain-containing protein 2; Presqualene diphosphate phosphatase | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IY26 |
|---|
Uniprot Id
Q8IY26
Target Species
Human
Target Name
PLPP6
Target Full Name
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6
Target Function
Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
PA-phosphatase related phosphoesterase family
Target Tissue Specificity
Widely expressed. Expressed in most organs, in particular gastrointestinal organs, spleen, placenta, kidney, thymus and brain.
Target Synonyms
PLPP6; PPAPDC2; Phospholipid phosphatase 6; Phosphatidic acid phosphatase type 2 domain-containing protein 2; PPAP2 domain-containing protein 2; Presqualene diphosphate phosphatase
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