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| Cat.No | ACP07373 | Target Name | GPR61 |
|---|---|---|---|
| Target Synonyms | GPR61; BALGR; GPCR3; G-protein coupled receptor 61; Biogenic amine receptor-like G-protein coupled receptor | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BZJ8 |
|---|
Uniprot Id
Q9BZJ8
Target Species
Human
Target Name
GPR61
Target Full Name
G-protein coupled receptor 61
Target Function
Orphan G-protein coupled receptor. Constitutively activates the G(s)-alpha/cAMP signaling pathway. Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization. May be involved in the regulation of food intake and body weight.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus. Also expressed in testis and T cells, B cells, and monocyte. Low expression in many other tissues. Widely expressed in the hippocampus (at protein level)
Target Synonyms
GPR61; BALGR; GPCR3; G-protein coupled receptor 61; Biogenic amine receptor-like G-protein coupled receptor
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