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Recombinant Human Probable tumor suppressor protein MN1 (MN1), Truncated

ACP18559

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Specifications

Cat.No	ACP18559	Target Name	MN1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q10571

Background Information

Uniprot Id

Q10571
Target Species

Human
Target Name

MN1
Target Full Name

Transcriptional activator MN1
Target Function

Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull. May play a role in tumor suppression (Probable).
Target Involvement

A chromosomal aberration involving MN1 may be a cause of acute myeloid leukemia (AML). Translocation t(12;22)(p13;q11) with ETV6.
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Widely expressed in fetal and adult tissues. Highest expression is observed in fetal brain and skeletal muscle, and adult skeletal muscle.
Target Synonyms

AA003644; AA009236; dJ353E16.2; Meningioma (disrupted in balanced translocation) 1; Meningioma (translocation balanced); Meningioma 1 ; meningioma chromosome region 1; MGCR; MGCR1; MGCR1-PEN; MN1; MN1_HUMAN; Probable tumor suppressor protein MN1; RGD1565571

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Recombinant Human Probable tumor suppressor protein MN1 (MN1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Probable tumor suppressor protein MN1 (MN1), Truncated Now

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