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| Cat.No | ACP11703 | Target Name | DONSON |
|---|---|---|---|
| Target Synonyms | DONSON; C21orf60Protein downstream neighbor of Son; B17 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-566 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NYP3 |
|---|
Uniprot Id
Q9NYP3
Target Species
Human
Target Name
DONSON
Target Full Name
Protein downstream neighbor of Son
Target Function
Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra-S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability.
Target Involvement
Microcephaly-micromelia syndrome (MIMIS); Microcephaly, short stature, and limb abnormalities (MISSLA)
Target Subcellular Location
Nucleus.
Target Protein Families
DONSON family
Target Tissue Specificity
Expressed in the brain, with higher levels in prenatal compared to adult brain.
Target Synonyms
DONSON; C21orf60Protein downstream neighbor of Son; B17
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