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| Cat.No | ACP17099 | Target Name | C1QTNF12 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 21-302 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5T7M4 |
|---|
Uniprot Id
Q5T7M4
Target Species
Human
Target Name
C1QTNF12
Target Full Name
Adipolin
Target Function
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue.
Target Subcellular Location
[Adipolin fC1QTNF12]: Secreted.; [Adipolin gC1QTNF12]: Secreted.
Target Protein Families
Adipolin/erythroferrone family
Target Tissue Specificity
Predominantly expressed by adipose tissues.
Target Synonyms
C1QTNF12; C1QDC2; CTRP12; FAM132AAdipolin; Adipose-derived insulin-sensitizing factor; C1q and TNF related protein 12; Complement C1q tumor necrosis factor-related protein 12) [Cleaved into: Adipolin fC1QTNF12; Adipolin fCTRP12; Adipolin full-length form); Adipolin gC1QTNF12; Adipolin cleaved form; Adipolin gCTRP12)]
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