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| Cat.No | ACP24433 | Target Name | ELFN1 |
|---|---|---|---|
| Target Synonyms | ELFN1; PPP1R28Protein ELFN1; Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1; Protein phosphatase 1 regulatory subunit 28 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P0C7U0 |
|---|
Uniprot Id
P0C7U0
Target Species
Human
Target Name
ELFN1
Target Full Name
Protein ELFN1
Target Function
Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses. Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Cell projection, dendrite.
Target Synonyms
ELFN1; PPP1R28Protein ELFN1; Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1; Protein phosphatase 1 regulatory subunit 28
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