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Recombinant Human Protein phosphatase 1G (PPM1G)

ACP21379

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21379 Target NamePPM1G
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range2-546Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO15355
Background Information
  • Uniprot Id

    O15355

  • Target Species

    Human

  • Target Name

    PPM1G

  • Target Full Name

    Protein phosphatase 1G

  • Target Subcellular Location

    Cytoplasm. Membrane; Lipid-anchor.

  • Target Protein Families

    PP2C family

  • Target Tissue Specificity

    Widely expressed. Most abundant in testis, skeletal muscle, and heart.

  • Target Synonyms

    MGC1675; MGC2870; OTTHUMP00000123426; PP2C; PP2C gamma; PP2C-gamma; PP2CG; PP2Cgamma; PPM1G; PPM1G_HUMAN; PPP2CG; Protein phosphatase 1C; Protein phosphatase 1G; Protein phosphatase 2 catalytic subunit gamma isoform; Protein phosphatase 2C gamma isoform ; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium dependent 1 gamma; Protein phosphatase magnesium-dependent 1 gamma; Protein phosphatase Mg2+/Mn2+ dependent 1G

  • Target Background

    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.

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