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| Cat.No | ACP21379 | Target Name | PPM1G |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-546 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O15355 |
|---|
Uniprot Id
O15355
Target Species
Human
Target Name
PPM1G
Target Full Name
Protein phosphatase 1G
Target Subcellular Location
Cytoplasm. Membrane; Lipid-anchor.
Target Protein Families
PP2C family
Target Tissue Specificity
Widely expressed. Most abundant in testis, skeletal muscle, and heart.
Target Synonyms
MGC1675; MGC2870; OTTHUMP00000123426; PP2C; PP2C gamma; PP2C-gamma; PP2CG; PP2Cgamma; PPM1G; PPM1G_HUMAN; PPP2CG; Protein phosphatase 1C; Protein phosphatase 1G; Protein phosphatase 2 catalytic subunit gamma isoform; Protein phosphatase 2C gamma isoform ; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium dependent 1 gamma; Protein phosphatase magnesium-dependent 1 gamma; Protein phosphatase Mg2+/Mn2+ dependent 1G
Target Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
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