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| Cat.No | ACP16850 | Target Name | VIRMA |
|---|---|---|---|
| Target Synonyms | DKFZp434I116; DKFZp781B2117; fSAP121; KIAA1429; MGC138493; MGC141940; MSTP054; Protein virilizer homolog; VIR_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q69YN4 |
|---|
Uniprot Id
Q69YN4
Target Species
Human
Target Name
VIRMA
Target Full Name
Protein virilizer homolog
Target Function
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon correlating with alternative polyadenylation (APA)
Target Subcellular Location
Nucleus speckle. Nucleus, nucleoplasm. Cytoplasm.
Target Protein Families
Vir family
Target Synonyms
DKFZp434I116; DKFZp781B2117; fSAP121; KIAA1429; MGC138493; MGC141940; MSTP054; Protein virilizer homolog; VIR_HUMAN
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