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| Cat.No | ACP10327 | Target Name | ZWILCH |
|---|---|---|---|
| Target Synonyms | FLJ10036; FLJ16343; homolog of Drosophila Zwilch; hZwilch; KNTC1AP; MGC111034; Protein zwilch homolog; ZWILC_HUMAN; zwilch; zwilch kinetochore protein; ZWILCH protein; Zwilch, homolog, kinetochore associated | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-591 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H900 |
|---|
Uniprot Id
Q9H900
Target Species
Human
Target Name
ZWILCH
Target Full Name
Protein zwilch homolog
Target Function
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Target Subcellular Location
Chromosome, centromere, kinetochore.
Target Protein Families
ZWILCH family
Target Synonyms
FLJ10036; FLJ16343; homolog of Drosophila Zwilch; hZwilch; KNTC1AP; MGC111034; Protein zwilch homolog; ZWILC_HUMAN; zwilch; zwilch kinetochore protein; ZWILCH protein; Zwilch, kinetochore associated, homolog
Target Background
Involved in protein localization to kinetochore. Located in kinetochore. Part of RZZ complex.
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