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| Cat.No | ACP23953 | Target Name | TRH |
|---|---|---|---|
| Target Synonyms | TRH; Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin) [Cleaved into: Thyrotropin-releasing hormone; TRH; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor; TRF)] | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 25-242 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P20396 |
|---|
Uniprot Id
P20396
Target Species
Human
Target Name
TRH
Target Full Name
Pro-thyrotropin-releasing hormone
Target Function
As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes.
Target Subcellular Location
Secreted.
Target Protein Families
TRH family
Target Tissue Specificity
Hypothalamus. Expressed in the hair follicle epithelium (at protein level).
Target Synonyms
TRH; Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin) [Cleaved into: Thyrotropin-releasing hormone; TRH; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor; TRF)]
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