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Recombinant Human Putative teratocarcinoma-derived growth factor 3 (TDGF1P3)

Human Putative teratocarcinoma-derived growth factor 3 (TDGF1P3) amino acids (31-188) with a 6xHis-tag at the N-terminus were expressed in?E. coli. The resulting protein is the recombinant full-length of mature human TDGF1P3 protein. Its purity is greater than 85% measured by SDS-PAGE analysis. It has a calculated molecular weight of 21.9 kDa. This recombinant TDGF1P3 protein may be used to generate specific antibodies or in the studies of TDGF1P3-related signal transduction. TDGF1P3 could play a role in the determination of the epiblastic cells that subsequently generate the mesoderm. It is also involved in the activation of the Nodal-dependent signaling pathway, which is essential for regional and cellular differentiation during embryonic development.

ACP05136

Human Putative teratocarcinoma-derived growth factor 3 (TDGF1P3) amino acids (31-188) with a 6xHis-tag at the N-terminus were expressed in?E. coli. The resulting protein is the recombinant full-length of mature human TDGF1P3 protein. Its purity is greater than 85% measured by SDS-PAGE analysis. It has a calculated molecular weight of 21.9 kDa. This recombinant TDGF1P3 protein may be used to generate specific antibodies or in the studies of TDGF1P3-related signal transduction.
TDGF1P3 could play a role in the determination of the epiblastic cells that subsequently generate the mesoderm. It is also involved in the activation of the Nodal-dependent signaling pathway, which is essential for regional and cellular differentiation during embryonic development.

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Specifications


Cat.No ACP05136 Target NameTDGF1P3
FormLiquid or Lyophilized powderExpression SystemE.coli
Expression Range31-188aaMol Weight21.9 kDa
Protein LengthFull Length of Mature ProteinPurityGreater than 85% as determined by SDS-PAGE.
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP51864
Background Information
  • Uniprot Id

    P51864

  • Target Species

    Human

  • Target Name

    CRIPTO3

  • Target Full Name

    Putative protein CRIPTO3

  • Target Function

    Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

  • Target Subcellular Location

    Cell membrane.

  • Target Protein Families

    EGF-CFC (Cripto-1/FRL1/Cryptic) family

  • Target Tissue Specificity

    Expressed weakly in lung, colon and breast. Expressed also strongly in primary cancer tissues; lung and colon cancers.

  • Target Research Area

    Others

  • Target Synonyms

    TDGF1P3; CRIPTO3; TDGF2; TDGF3; Putative teratocarcinoma-derived growth factor 3; Cripto-3 growth factor; Epidermal growth factor-like cripto protein CR3; Teratocarcinoma-derived growth factor 1 pseudogene 3

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