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| Cat.No | ACP21092 | Target Name | DNAJC6 |
|---|---|---|---|
| Target Synonyms | DNAJC6; KIAA0473; Putative tyrosine-protein phosphatase auxilin; EC 3.1.3.48; DnaJ homolog subfamily C member 6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75061 |
|---|
Uniprot Id
O75061
Target Species
Human
Target Name
DNAJC6
Target Full Name
Auxilin
Target Function
Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons.
Target Involvement
Parkinson disease 19A, juvenile-onset (PARK19A); Parkinson disease 19B, early-onset (PARK19B)
Target Tissue Specificity
Expressed in various brain regions, including cerebellum, corpus callosum, cortex, striatum, brainstem, pons, putamen, spinal cord and substantia nigra. Very low expression in non-neural tissues such as leukocytes, liver, adipose tissue, skeletal muscle a
Target Synonyms
DNAJC6; KIAA0473; Putative tyrosine-protein phosphatase auxilin; EC 3.1.3.48; DnaJ homolog subfamily C member 6
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