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| Cat.No | ACP18161 | Target Name | RAB32 |
|---|---|---|---|
| Target Synonyms | member RAS oncogene family; RAB32_HUMAN; Ras related protein Rab32; Ras-related protein Rab-32, RAB32; RAB32 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-225 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13637 |
|---|
Uniprot Id
Q13637
Target Species
Human
Target Name
RAB32
Target Full Name
Ras-related protein Rab-32
Target Function
Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
Target Subcellular Location
Mitochondrion. Mitochondrion outer membrane; Lipid-anchor. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Melanosome membrane.
Target Protein Families
Small GTPase superfamily, Rab family
Target Tissue Specificity
Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.
Target Synonyms
RAB32; RAB32, member RAS oncogene family; RAB32_HUMAN; Ras related protein Rab32; Ras-related protein Rab-32
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