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| Cat.No | ACP16263 | Target Name | RAET1G |
|---|---|---|---|
| Target Synonyms | RAET1G; ULBP5; UL-16 binding protein 5; Retinoic acid early transcript 1G protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6H3X3 |
|---|
Uniprot Id
Q6H3X3
Target Species
Human
Target Name
RAET1G
Target Full Name
UL-16 binding protein 5
Target Function
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.; Down-regulates the expression of KLRK1 and stimulates natural killer cells to secrete IFNG.; Stimulates natural killer cells to secrete IFNG.
Target Subcellular Location
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum.; [Isoform 2]: Secreted.
Target Protein Families
MHC class I family
Target Tissue Specificity
Isoform 1 is highly expressed in colon and in a number of tumor cell lines and highly restricted in normal tissues. Both isoforms are frequently expressed in cell lines derived from epithelial cancers, and in primary breast cancers.
Target Synonyms
RAET1G; ULBP5; UL-16 binding protein 5; Retinoic acid early transcript 1G protein
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