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Recombinant Human Retinol dehydrogenase 10 (RDH10), Truncated

ACP15006

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15006 Target NameRDH10
Target SynonymsRDH 10; RDH10; RDH10_HUMAN; Retinol dehydrogenase 10 (all trans); Retinol dehydrogenase 10; SDR16C4; Short chain dehydrogenase/reductase family 16C member 4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8IZV5
Background Information
  • Uniprot Id

    Q8IZV5

  • Target Species

    Human

  • Target Name

    RDH10

  • Target Full Name

    Retinol dehydrogenase 10

  • Target Function

    Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.

  • Target Subcellular Location

    Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    Short-chain dehydrogenases/reductases (SDR) family

  • Target Tissue Specificity

    Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle.

  • Target Synonyms

    RDH 10; RDH10; RDH10_HUMAN; Retinol dehydrogenase 10 (all trans); Retinol dehydrogenase 10; SDR16C4; Short chain dehydrogenase/reductase family 16C member 4

  • Target Background

    This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development.

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