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Recombinant Human Retinol dehydrogenase 16 (RDH16), Truncated

ACP06360

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06360 Target NameRDH16
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO75452
Background Information
  • Uniprot Id

    O75452

  • Target Species

    Human

  • Target Name

    RDH16

  • Target Full Name

    Retinol dehydrogenase 16

  • Target Function

    Oxidoreductase with a preference for NAD. Oxidizes all-trans-retinol, 9-cis-retinol, 11-cis-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Oxidizes also 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. Can also catalyze the reverse reaction.

  • Target Subcellular Location

    Microsome membrane. Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    Short-chain dehydrogenases/reductases (SDR) family

  • Target Tissue Specificity

    Highly expressed in adult liver (at protein level). Detected in endometrium, liver and foreskin. Detected in the spineous layers of adult skin, and at lower levels in basal and granular skin layers. Detected in fetal liver and lung.

  • Target Synonyms

    RDH16; RODH4; SDR9C8; Retinol dehydrogenase 16; Human epidermal retinol dehydrogenase; hRDH-E; Microsomal NAD(+-dependent retinol dehydrogenase 4; RoDH-4; Short chain dehydrogenase/reductase family 9C member 8; Sterol/retinol dehydrogenase

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