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| Cat.No | ACP17276 | Target Name | RILPL1 |
|---|---|---|---|
| Target Synonyms | GOSPEL; MGC105128 ; MGC99793; Rab interacting lysosomal protein like 1; Rab-interacting lysosomal-like protein 1; RILP like protein 1; RILP-like protein 1; RILPL 1; rilpl1; RIPL1_HUMAN; RLP1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-403 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5EBL4 |
|---|
Uniprot Id
Q5EBL4
Target Species
Human
Target Name
RILPL1
Target Full Name
RILP-like protein 1
Target Function
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution. Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis.
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
Target Protein Families
RILPL family
Target Tissue Specificity
Widely expressed. Expressed at lower level in liver and kidney.
Target Synonyms
GOSPEL; MGC105128 ; MGC99793; Rab interacting lysosomal protein like 1; Rab-interacting lysosomal-like protein 1; RILP like protein 1; RILP-like protein 1; RILPL 1; rilpl1; RIPL1_HUMAN; RLP1
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