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Recombinant Human RNA (guanine-9-)-methyltransferase domain-containing protein 2 (RG9MTD2)

ACP13622

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13622 Target NameTRMT10A
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-339Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TBZ6
Background Information
  • Uniprot Id

    Q8TBZ6

  • Target Species

    Human

  • Target Name

    TRMT10A

  • Target Full Name

    tRNA methyltransferase 10 homolog A

  • Target Function

    S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.

  • Target Involvement

    Microcephaly, short stature, and impaired glucose metabolism 1 (MSSGM1)

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Protein Families

    Class IV-like SAM-binding methyltransferase superfamily, TRM10 family

  • Target Tissue Specificity

    Expressed in embryonic and fetal brain. It is expressed throughout the dorsal telencephalon at 8 and 11 weeks of gestation, with highest expression in ventricular zone and marginal zone. Detected in cerebellar cortex and nuclei, but not in dorsal telencep

  • Target Synonyms

    FLJ20325; MGC27034; OTTHUMP00000220442; OTTHUMP00000220443; RG9D2_HUMAN; RG9MTD 2; Rg9mtd2; RNA (guanine-9-) methyltransferase domain containing 2; RNA (guanine-9-)-methyltransferase domain-containing protein 2; RNA (guanine-9-)methyltransferase domain containing protein 2; TRM10

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