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| Cat.No | ACP09967 | Target Name | SARDH |
|---|---|---|---|
| Target Synonyms | SARDH; DMGDHL1; Sarcosine dehydrogenase; mitochondrial; SarDH; EC 1.5.8.3; BPR-2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UL12 |
|---|
Uniprot Id
Q9UL12
Target Species
Human
Target Name
SARDH
Target Full Name
Sarcosine dehydrogenase, mitochondrial
Target Involvement
Sarcosinemia (SARCOS)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
GcvT family
Target Synonyms
SARDH; DMGDHL1; Sarcosine dehydrogenase; mitochondrial; SarDH; EC 1.5.8.3; BPR-2
Target Background
This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described.
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