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| Cat.No | ACP13564 | Target Name | SEC14L1 |
|---|---|---|---|
| Target Synonyms | SEC14L1; SEC14L; SEC14-like protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-715 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92503 |
|---|
Uniprot Id
Q92503
Target Species
Human
Target Name
SEC14L1
Target Full Name
SEC14-like protein 1
Target Function
May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.
Target Subcellular Location
Cytoplasm. Golgi apparatus.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
SEC14L1; SEC14L; SEC14-like protein 1
Notification