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Recombinant Human Semaphorin-4C (SEMA4C), Truncated

ACP12146

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Specifications

Cat.No	ACP12146	Target Name	SEMA4C
Target Synonyms	(semaphorin) 4C; SEMA4C; SEMACL1; SEMAF; SEMAI; Semaphorin-4C; UNQ5855/PRO34487, immunoglobulin domain (Ig), KIAA1739; M-SEMA-F; S4c; SEM4C_HUMAN; Sema domain, transmembrane domain (TM) and short cytoplasmic domain	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9C0C4

Background Information

Uniprot Id

Q9C0C4
Target Species

Human
Target Name

SEMA4C
Target Full Name

Semaphorin-4C
Target Function

Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Target Subcellular Location

Cell junction, synapse, postsynaptic density membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein.
Target Protein Families

Semaphorin family
Target Synonyms

KIAA1739; M-SEMA-F; S4c; SEM4C_HUMAN; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C; SEMA4C; SEMACL1; SEMAF; SEMAI; Semaphorin-4C; UNQ5855/PRO34487
Target Background

Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Involved in muscle cell differentiation and positive regulation of stress-activated MAPK cascade. Located in extracellular space.

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Recombinant Human Semaphorin-4C (SEMA4C), Truncated

Specifications

Immunogen Information

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