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Recombinant Human SLIT-ROBO Rho GTPase-activating protein 1 (SRGAP1), Truncated

ACP15589

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15589 Target NameSRGAP1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ7Z6B7
Background Information
  • Uniprot Id

    Q7Z6B7

  • Target Species

    Human

  • Target Name

    SRGAP1

  • Target Full Name

    SLIT-ROBO Rho GTPase-activating protein 1

  • Target Function

    GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

  • Target Involvement

    Thyroid cancer, non-medullary, 2 (NMTC2)

  • Target Tissue Specificity

    Expressed in brain, lung, kidney, and testis.

  • Target Synonyms

    4930572H05Rik; ARHGAP13; FLJ22166; KIAA1304; RGD1566260; Rho GTPase activating protein 13; Rho GTPase-activating protein 13; SLIT ROBO Rho GTPase activating protein 1; SLIT-ROBO Rho GTPase-activating protein 1; SRGAP 1; srGAP1; SRGP1_HUMAN

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