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| Cat.No | ACP05486 | Target Name | SLC6A9 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P48067 |
|---|
Uniprot Id
P48067
Target Species
Human
Target Name
SLC6A9
Target Full Name
Sodium- and chloride-dependent glycine transporter 1
Target Function
Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.
Target Involvement
Glycine encephalopathy with normal serum glycine (GCENSG)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A9 subfamily
Target Tissue Specificity
Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain.
Target Synonyms
glycine transporter 1; Glyt 1; GlyT-1; GlyT1; SC6A9_HUMAN; SLC6A9; Sodium and chloride dependent glycine transporter 1; Sodium- and chloride-dependent glycine transporter 1; Solute carrier family 6 member 9
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