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| Cat.No | ACP05988 | Target Name | SLC22A9 |
|---|---|---|---|
| Target Synonyms | SLC22A9; hOAT4; OAT7; UST3; Solute carrier family 22 member 9; Organic anion transporter 7 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IVM8 |
|---|
Uniprot Id
Q8IVM8
Target Species
Human
Target Name
SLC22A9
Target Full Name
Organic anion transporter 7
Target Function
Sodium-independent organic anion transporter which exhibits high specificity for sulfated conjugates of xenobiotics and steroid hormones. It is also specifically activated by 3 to 5 carbons-containing short-chain fatty acids/SCFAs, including propionate, butyrate and valerate. May operate the exchange of sulfated organic components against short-chain fatty acids/SCFAs at the sinusoidal membrane of hepatocytes.
Target Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein. Note=Enriched at the sinusoidal part of the plasma membrane.
Target Protein Families
Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family
Target Tissue Specificity
Specifically expressed in liver by hepatocytes (at protein level).
Target Synonyms
SLC22A9; hOAT4; OAT7; UST3; Solute carrier family 22 member 9; Organic anion transporter 7
Target Background
Enables anion:anion antiporter activity; short-chain fatty acid transmembrane transporter activity; and sodium-independent organic anion transmembrane transporter activity. Involved in hormone transport; short-chain fatty acid import; and sodium-independent organic anion transport. Located in basolateral plasma membrane.
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