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Recombinant Human Sphingosine-1-phosphate phosphatase 2 (SGPP2), Truncated

ACP05981

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Specifications

Cat.No	ACP05981	Target Name	SGPP2
Target Synonyms	SGPP2; Sphingosine-1-phosphate phosphatase 2; SPPase2; Spp2; hSPP2; EC 3.1.3.-; Sphingosine-1-phosphatase 2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IWX5

Background Information

Uniprot Id

Q8IWX5
Target Species

Human
Target Name

SGPP2
Target Full Name

Sphingosine-1-phosphate phosphatase 2
Target Function

Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation.
Target Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families

Type 2 lipid phosphate phosphatase family
Target Tissue Specificity

Expressed strongly in kidney and heart, followed by brain, colon, small intestine and lung. Not detected in skeletal muscle, thymus, spleen, liver, placenta, and peripheral blood leukocytes.
Target Synonyms

SGPP2; Sphingosine-1-phosphate phosphatase 2; SPPase2; Spp2; hSPP2; EC 3.1.3.-; Sphingosine-1-phosphatase 2

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Recombinant Human Sphingosine-1-phosphate phosphatase 2 (SGPP2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Sphingosine-1-phosphate phosphatase 2 (SGPP2), Truncated Now

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