Recombinant Human Synaptogyrin-1 (SYNGR1)

Uniprot Id

O43759

Target Species

Human

Target Name

SYNGR1

Target Full Name

Synaptogyrin-1

Target Function

May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation. Involved in the regulation of short-term and long-term synaptic plasticity.

Target Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Melanosome.

Target Protein Families

Synaptogyrin family

Target Research Area

Neuroscience

Target Synonyms

SNG1_HUMAN; Synaptogyrin-1; Syngr1

Target Background

This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified.