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| Cat.No | ACP09735 | Target Name | SNCAIP |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y6H5 |
|---|
Uniprot Id
Q9Y6H5
Target Species
Human
Target Name
SNCAIP
Target Full Name
Synphilin-1
Target Function
Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1.
Target Involvement
Parkinson disease (PARK)
Target Subcellular Location
Cytoplasm. Note=Detected in cytoplasmic inclusion bodies, together with SNCA.
Target Tissue Specificity
Detected in brain (at protein level). Widely expressed, with highest levels in brain, heart and placenta.
Target Synonyms
Alpha synuclein interacting protein; Alpha-synuclein-interacting protein; MGC39814; SNCAIP; SNCAP_HUMAN; Sph1; Synphilin-1; Synphilin1; Synuclein alpha interacting protein (synphilin); Synuclein alpha interacting protein; SYPH 1
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