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| Cat.No | ACP10570 | Target Name | TENM2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NT68 |
|---|
Uniprot Id
Q9NT68
Target Species
Human
Target Name
TENM2
Target Full Name
Teneurin-2
Target Function
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Induces homophilic cell-cell adhesion. May function as a cellular signal transducer.; Acts as a ligand of the ADGRL1 receptor. Mediates axon guidance and heterophilic cell-cell adhesion.; Induces gene transcription inhibition.
Target Subcellular Location
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, growth cone. Cell junction, synapse, postsynaptic cell membrane; Single-pass membrane protein. Cell junction, synapse, synaptosome.; [Isoform 2]: Cell membrane. Note=Colocalizes with ADGRL1 across intercellular junctions.; [Ten-2 intracellular domain]: Nucleus, PML body.
Target Protein Families
Tenascin family, Teneurin subfamily
Target Tissue Specificity
Highly expressed in heart, followed by brain, liver, kidney and fetal brain and weakly expressed in lung and testis. No expression was detected in skeletal muscle, pancreas, spleen, ovary and fetal liver.
Target Synonyms
TENM2; KIAA1127; ODZ2; TNM2; Teneurin-2; Ten-2; Protein Odd Oz/ten-m homolog 2; Tenascin-M2; Ten-m2; Teneurin transmembrane protein 2) [Cleaved into: Ten-2; soluble form; Ten-2 intracellular domain; Ten-2 ICD)]
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