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| Cat.No | ACP15714 | Target Name | TTC21B |
|---|---|---|---|
| Target Synonyms | TTC21B; IFT139; KIAA1992; Nbla10696; Tetratricopeptide repeat protein 21B; TPR repeat protein 21B; Intraflagellar transport 139 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z4L5 |
|---|
Uniprot Id
Q7Z4L5
Target Species
Human
Target Name
TTC21B
Target Full Name
Tetratricopeptide repeat protein 21B
Target Function
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Essential for retrograde trafficking of IFT-1, IFT-B and GPCRs. Negatively modulates the SHH signal transduction.
Target Involvement
Nephronophthisis 12 (NPHP12); Short-rib thoracic dysplasia 4 with or without polydactyly (SRTD4); Joubert syndrome 11 (JBTS11)
Target Subcellular Location
Cytoplasm, cytoskeleton, cilium axoneme.
Target Protein Families
TTC21 family
Target Synonyms
TTC21B; IFT139; KIAA1992; Nbla10696; Tetratricopeptide repeat protein 21B; TPR repeat protein 21B; Intraflagellar transport 139 homolog
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