Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The product CSB-YP023317HU is a recombinant human transcobalamin-1 (TCN1) expressed in the yeast. Its target gene sequence corresponds to amino acids 24-433 of the human TCN1. The 6xHis-tag is fused to the protein at the N-terminus. Its purity is greater than 90% determined by SDS-PAGE. It migrated to the molecular weight band of 45-50 kDa. This recombinant TCN1 protein is a full-length of the mature protein. It is available now. The target protein TCN1 is a glycoprotein produced by the salivary glands of the mouth. The primary function of this protein is to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a Haptocorrin-Vitamin B12 complex.
The product CSB-YP023317HU is a recombinant human transcobalamin-1 (TCN1) expressed in the yeast. Its target gene sequence corresponds to amino acids 24-433 of the human TCN1. The 6xHis-tag is fused to the protein at the N-terminus. Its purity is greater than 90% determined by SDS-PAGE. It migrated to the molecular weight band of 45-50 kDa. This recombinant TCN1 protein is a full-length of the mature protein. It is available now. The target protein TCN1 is a glycoprotein produced by the salivary glands of the mouth. The primary function of this protein is to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a Haptocorrin-Vitamin B12 complex.
| Cat.No | ACP04822 | Target Name | TCN1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | Yeast |
| Expression Range | 24-433aa | Mol Weight | 47.6kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P20061 |
|---|
Uniprot Id
P20061
Target Species
Human
Target Name
TCN1
Target Full Name
Transcobalamin-1
Target Function
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
Target Subcellular Location
Secreted.
Target Protein Families
Eukaryotic cobalamin transport proteins family
Target Tissue Specificity
Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils.
Target Research Area
Signal Transduction
Target Synonyms
Haptocorin; Haptocorrin; HC; OTTHUMP00000235879; TC 1; TC I; TC-1; TC1; TCI; TCN 1; TCN1; TCO1_HUMAN; Transcobalamin 1; Transcobalamin I; Transcobalamin-1; Transcobalamin1; TranscobalaminI; Vitamin B12 binding protein; Vitamin B12 binding protein R binder family
Target Background
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
