Recombinant Human Transcription factor AP-2-delta (TFAP2D)

Uniprot Id

Q7Z6R9

Target Species

Human

Target Name

TFAP2D

Target Full Name

Transcription factor AP-2-delta

Target Function

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

Target Subcellular Location

Nucleus.

Target Protein Families

AP-2 family

Target Tissue Specificity

Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas.

Target Synonyms

activating enhancer binding protein 2 beta like 1; activating enhancer binding protein 2 delta; Activating enhancer-binding protein 2-delta; AP 2 like; AP2 delta; AP2 like; AP2-delta; AP2D_HUMAN; TFAP2BL1; tfap2d; transcription factor AP 2 beta like 1; transcription factor AP 2 delta (activating enhancer binding protein 2 delta); transcription factor AP 2 delta; transcription factor AP-2 delta (activating enhancer binding protein 2 delta); Transcription factor AP-2-beta-like 1; Transcription factor AP-2-delta; transcription factor AP2 beta like 1; transcription factor AP2 delta (activating enhancer binding protein 2 delta); transcription factor AP2 delta