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Recombinant Human Transcription factor SOX-1 (SOX1)

ACP21430

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21430 Target NameSOX1
Target SynonymsSex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-391
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO00570
Background Information
  • Uniprot Id

    O00570

  • Target Species

    Human

  • Target Name

    SOX1

  • Target Full Name

    Transcription factor SOX-1

  • Target Function

    Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Mainly expressed in the developing central nervous system.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    Sex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1

  • Target Background

    This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.

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