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| Cat.No | ACP15973 | Target Name | TMPRSS11A |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZMR5 |
|---|
Uniprot Id
Q6ZMR5
Target Species
Human
Target Name
TMPRSS11A
Target Full Name
Transmembrane protease serine 11A
Target Function
Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Protein Families
Peptidase S1 family
Target Tissue Specificity
Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers.
Target Research Area
Cell cycle
Target Synonyms
Airway trypsin-like protease 1; ECRG1; epidermal type II transmembrane serine protease; Epidermal type-II transmembrane serine protease; Esophageal cancer-susceptibility gene 1 protein; TM11A_HUMAN; Tmprss11a; TMPRSS11A protein; Transmembrane protease serine 11A
Target Background
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Predicted to be integral component of plasma membrane.
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