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| Cat.No | ACP07237 | Target Name | TMEM70 |
|---|---|---|---|
| Target Synonyms | mitochondrial, TMEM70; Transmembrane protein 70 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BUB7 |
|---|
Uniprot Id
Q9BUB7
Target Species
Human
Target Name
TMEM70
Target Full Name
Transmembrane protein 70, mitochondrial
Target Function
Involved in biogenesis of mitochondrial ATP synthase.
Target Involvement
Mitochondrial complex V deficiency, nuclear 2 (MC5DN2)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
TMEM70 family
Target Synonyms
TMEM70; Transmembrane protein 70, mitochondrial
Target Background
This gene likely encodes a mitochondrial membrane protein. The encoded protein may play a role in biogenesis of mitochondrial ATP synthase. Mutations in this gene have been associated with neonatal mitochondrial encephalocardiomyopathy due to ATP synthase deficiency. Alternatively spliced transcript variants have been described.
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