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Recombinant Human Transmembrane protein PVRIG (PVRIG), Truncated

ACP08275

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Specifications

Cat.No	ACP08275	Target Name	PVRIG
Target Synonyms	PVRIG; C7orf15; Transmembrane protein PVRIG; CD112 receptor; CD112R; Poliovirus receptor-related immunoglobulin domain-containing protein	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6DKI7

Background Information

Uniprot Id

Q6DKI7
Target Species

Human
Target Name

PVRIG
Target Full Name

Transmembrane protein PVRIG
Target Function

Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Tissue Specificity

Expressed in some types of immune cells. Expressed at low levels on the surface of freshly isolated T-cells and natural killer (NK) cells, predominantly on CD8+ T-cells (mainly memory/effector, but not naive cells) and on both CD16+ and CD16- NK cells. T-
Target Synonyms

PVRIG; C7orf15; Transmembrane protein PVRIG; CD112 receptor; CD112R; Poliovirus receptor-related immunoglobulin domain-containing protein
Target Background

Enables phosphatase binding activity and signaling receptor activity. Involved in negative regulation of T cell receptor signaling pathway. Located in plasma membrane.

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Recombinant Human Transmembrane protein PVRIG (PVRIG), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Transmembrane protein PVRIG (PVRIG), Truncated Now

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